Effectiveness of Clonazepam on Sleep Quality on Maintenance Haemodialysis Patients
*Dr. Estiak Ahmed
Senior Lecturer, Department of Pharmacology and Therapeutics, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh. estiak2018@gmail.com
Dr. Abu Tareq Md Rashel
Assistant Professor, Department of Pharmacology and Therapeutics, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh.
Dr. Nurjahan Ferdoush
Assistant Professor, Department of Pharmacology and Therapeutics, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh
Dr. Amirun Nahar
Assistant Professor, Department of Pharmacology and Therapeutics, Z. H. Sikder Women’s Medical College, Dhaka 1209, Bangladesh.
Dr. Tinni Rani Paul
Assistant Professor, Department of Pharmacology and Therapeutics, Park View Medical College, Sylhet 3100, Bangladesh.
Dr. Mohammad Nurunnabi
Assistant Professor, Department of Community Medicine, Sylhet Women’s Medical College, Sylhet 3100, Bangladesh. nur.somch@gmail.com
Keywords: Clonazepam, effectiveness, sleep quality, haemodialysis patients, Bangladesh.
Abstract
Background: Patients receiving dialysis for chronic kidney disease (CKD) frequently experience sleep disorders. As a result, quality of life is degraded. These patients frequently utilize sedative-hypnotic drugs to maintain theirsleep quality.
Methods: A cross-sectional study was done to assess the efficacy of Clonazepam on sleep quality of patients on maintenance hemodialysis in the Department of Nephrology, Sylhet MAG Osmani Medical College Hospital. A pretested semi-structured questionnaire was used for interviewing 50 CKD patients. The patients’ sleep quality was evaluated by using the PSQI scale.
Results: The mean age of the Clonazepam treated group was 60.5±5.6 years and the male was predominant (56.0%). Two-thirds of the patients (65.3%) were improved sleep quality. Sleep quality was good among the age group 51-60 years (86.4%) and male patients (57.1%). The mean of PSQI scores was 17.1±0.9 at baseline before the initiation of treatment which decreased to 11.8±1.3 after the completion of 2 weeks of treatment. The difference from the baseline to the end point of treatment was significant (p<0.05).
Conclusion: The study revealed that Clonazepam is effectively improving the sleep quality of hemodialysis patients.
M Abdur Rahim Medical College Journal, 2023 Jul; 16(2)